Swissregulon Database contains genome-wide annotations of regulatory sites. The predictions are based on Bayesian probabilistic analysis of a combination of input information including:
- Experimentally determined binding sites reported in the literature.
- Known sequence-specificities of transcription factors.
- ChIP-chip and ChIP-seq data.
- Alignments of orthologous non-coding regions.
Predictions were made using the PhyloGibbs, MotEvo, IRUS and ISMARA algorithms developed in our group, depending on the data available for each organism. Annotations can be viewed in a Gbrowse genome browser and can also be downloaded in flat file format.
Please cite this site as following:
SwissRegulon, a database of genome-wide annotations of regulatory sites: recent updates.
Mikhail Pachkov, Piotr J. Balwierz, Evgeniy Ozonov and Erik van Nimwegen
Nucleic Acids Research, 2013, Vol. 41, Database issue D214-D220