Swissregulon Database contains genome-wide annotations of regulatory sites. The predictions are based on Bayesian probabilistic analysis of a combination of input information including:
- Experimentally determined binding sites reported in the literature.
- Known sequence-specificities of transcription factors.
- ChIP-chip and ChIP-seq data.
- Alignments of orthologous non-coding regions.
Predictions were made using the PhyloGibbs, MotEvo, IRUS and ISMARA algorithms developed in our group, depending on the data available for each organism. Annotations can be viewed in a Gbrowse genome browser and can also be downloaded in flat file format.
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